Research workbench
AlphaFold monomer V2.0 prediction for RHO1 guanine nucleotide exchange factor 3 (Q9Y7U5)
Analyse AlphaFold monomer V2.0 prediction for RHO1 guanine nucleotide exchange factor 3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9Y7U5
- Type
- protein
- Length
- 1,275 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- RHO1 guanine nucleotide exchange factor 3
- UniProt
- Q9Y7U5
- Pockets
- 16 · best druggability 0.73
Structure
1 distinct chain · 25% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RHO1 guanine nucleotide exchange factor 3 | protein | 1275 | 25% helix, 20% strand | Q9Y7U5 |
Pockets
16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 92 | 0.73 | 0.96 | 24 | empty |
| 2 | 712 | 0.72 | 0.78 | 64 | empty |
| 3 | 370 | 0.65 | 0.79 | 43 | empty |
| 4 | 470 | 0.63 | 0.76 | 38 | empty |
| 5 | 206 | 0.48 | 0.75 | 26 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y7U5
- Elsewhere: UniProt Q9Y7U5 · AlphaFold DB Q9Y7U5
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