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AlphaFold monomer V2.0 prediction for rab GTPase-activating protein 1 (A2AWA9)

Analyse AlphaFold monomer V2.0 prediction for rab GTPase-activating protein 1 (A2AWA9) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A2AWA9
Type
protein
Length
1,064 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xA5679Ea923b25F9e26b7597F1E5fD2be7f1A6Ad9
Molecule
Rab GTPase-activating protein 1
UniProt
A2AWA9
Pockets
8 · best druggability 0.62

Structure

1 distinct chain · 44% helix, 16% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARab GTPase-activating protein 1protein106444% helix, 16% strandA2AWA9

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15450.620.7548empty
23640.590.7646empty
31570.470.7734empty
41000.380.7518empty
5740.360.7620empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

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