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AlphaFold monomer V2.0 prediction for DNA repair and recombination protein rada (O74036)

Analyse AlphaFold monomer V2.0 prediction for DNA repair and recombination protein rada… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O74036
Type
protein
Length
349 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB44F19a0cb161828322eEEd13F55d4C3C34938d2
Molecule
DNA repair and recombination protein rada
UniProt
O74036
Pockets
4 · best druggability 0.35

Structure

1 distinct chain · 39% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA repair and recombination protein radaprotein34939% helix, 19% strandO74036

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1780.350.7618empty
2790.340.7516empty
3580.280.7415empty
4540.240.7215empty

Compared structures

  • 1PZN · RAD51 (rada) · an experimental structure of the same protein · chain A against A, TM-score 0.72
  • 1PZN · Rad51 (RadA) · an experimental structure of the same protein · chain A against A, TM-score 0.72
  • 5JEC · Apo-structure of humanised RadA-mutant humRadA33F · an experimental structure of the same protein · chain A against B, TM-score 0.65
  • 5JEC · Apo-structure of humanised rada-mutant HUMRADA33F · an experimental structure of the same protein · chain A against B, TM-score 0.65
  • 5JED · Apo-structure of humanised RadA-mutant humRadA28 · an experimental structure of the same protein · chain A against A, TM-score 0.64
  • 5JED · Apo-structure of humanised rada-mutant HUMRADA28 · an experimental structure of the same protein · chain A against A, TM-score 0.64
  • 6XTW · HUMRADA33F in complex with peptidic inhibitor 6 · an experimental structure of the same protein · chain A against B, TM-score 0.64
  • 6XTW · HumRadA33F in complex with peptidic inhibitor 6 · an experimental structure of the same protein · chain A against B, TM-score 0.64

Analyse

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