Research workbench
AlphaFold monomer V2.0 prediction for presenilin-2 (O12977)
Analyse AlphaFold monomer V2.0 prediction for presenilin-2 (O12977) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O12977
- Type
- protein
- Length
- 449 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbDA05C32aD6eE153C8C5A78dfa48d7Ba25694fea
- Molecule
- Presenilin-2
- UniProt
- O12977
- Pockets
- 3 · best druggability 0.79
Structure
1 distinct chain · 57% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Presenilin-2 | protein | 449 | 57% helix, 1% strand | O12977 |
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1171 | 0.79 | 0.80 | 73 | empty |
| 2 | 349 | 0.60 | 0.77 | 39 | empty |
| 3 | 170 | 0.58 | 0.82 | 27 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O12977
- Elsewhere: UniProt O12977 · AlphaFold DB O12977
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