Research workbench
AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase 2-a (Q5Z8Q9)
Analyse AlphaFold monomer V2.0 prediction for poly [ADP-ribose] polymerase 2-a (Q5Z8Q9) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q5Z8Q9
- Type
- protein
- Length
- 660 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xd3D09c70A651Fc18Cc83B08E783c20f3249a5Be2
- Molecule
- Poly [ADP-ribose] polymerase 2-a
- UniProt
- Q5Z8Q9
- Pockets
- 6 · best druggability 0.78
Structure
1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Poly [ADP-ribose] polymerase 2-a | protein | 660 | 36% helix, 21% strand | Q5Z8Q9 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 463 | 0.78 | 0.86 | 49 | empty |
| 2 | 697 | 0.69 | 0.77 | 65 | empty |
| 3 | 195 | 0.50 | 0.77 | 22 | empty |
| 4 | 154 | 0.49 | 0.78 | 27 | empty |
| 5 | 59 | 0.35 | 0.77 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5Z8Q9
- Elsewhere: UniProt Q5Z8Q9 · AlphaFold DB Q5Z8Q9
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