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AlphaFold monomer V2.0 prediction for pre-mRNA-splicing ATP-dependent RNA helicase prp-28 (Q7SEL0)

Analyse AlphaFold monomer V2.0 prediction for pre-mRNA-splicing ATP-dependent RNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q7SEL0
Type
protein
Length
728 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
Molecule
Pre-mRNA-splicing ATP-dependent RNA helicase prp-28
UniProt
Q7SEL0
Pockets
8 · best druggability 0.58

Structure

1 distinct chain · 43% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-mRNA-splicing ATP-dependent RNA helicase prp-28protein72843% helix, 9% strandQ7SEL0

Pockets

8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12080.580.8036empty
22060.580.8131empty
3630.500.8516empty
4910.420.7815empty
51160.400.7517empty

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