Research workbench
AlphaFold monomer V2.0 prediction for pre-mRNA-splicing ATP-dependent RNA helicase PRP28 (P0CQ88)
Analyse AlphaFold monomer V2.0 prediction for pre-mRNA-splicing ATP-dependent RNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P0CQ88
- Type
- protein
- Length
- 738 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xB35df660264f41795De49C83276C108A4ba91ADE
- Molecule
- Pre-mRNA-splicing ATP-dependent RNA helicase PRP28
- UniProt
- P0CQ88
- Pockets
- 5 · best druggability 0.73
Structure
1 distinct chain · 43% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing ATP-dependent RNA helicase PRP28 | protein | 738 | 43% helix, 9% strand | P0CQ88 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 655 | 0.73 | 0.80 | 74 | empty |
| 2 | 230 | 0.56 | 0.78 | 41 | empty |
| 3 | 124 | 0.40 | 0.75 | 15 | empty |
| 4 | 50 | 0.36 | 0.80 | 14 | empty |
| 5 | 102 | 0.36 | 0.74 | 23 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0CQ88
- Elsewhere: UniProt P0CQ88 · AlphaFold DB P0CQ88
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