Research workbench
AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor ATP- dependent RNA helicase PRP22 (O42643)
Analyse AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor ATP- dependent… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O42643
- Type
- protein
- Length
- 1,168 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22
- UniProt
- O42643
- Pockets
- 12 · best druggability 0.85
Structure
1 distinct chain · 41% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22 | protein | 1168 | 41% helix, 15% strand | O42643 |
Pockets
12 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 962 | 0.85 | 0.86 | 104 | empty |
| 2 | 831 | 0.76 | 0.80 | 69 | empty |
| 3 | 168 | 0.68 | 0.87 | 29 | empty |
| 4 | 466 | 0.67 | 0.79 | 46 | empty |
| 5 | 499 | 0.67 | 0.78 | 61 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O42643
- Elsewhere: UniProt O42643 · AlphaFold DB O42643
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