Research workbench
AlphaFold monomer V2.0 prediction for prominin-1 (O54990)
Analyse AlphaFold monomer V2.0 prediction for prominin-1 (O54990) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O54990
- Type
- protein
- Length
- 867 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x98e22253e31B07cB0618d7388D8e56673A1A11dF
- Molecule
- Prominin-1
- UniProt
- O54990
- Pockets
- 10 · best druggability 0.76
Structure
1 distinct chain · 74% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prominin-1 | protein | 867 | 74% helix, 1% strand | O54990 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 646 | 0.76 | 0.81 | 54 | empty |
| 2 | 197 | 0.53 | 0.77 | 22 | empty |
| 3 | 254 | 0.52 | 0.75 | 32 | empty |
| 4 | 213 | 0.48 | 0.74 | 37 | empty |
| 5 | 108 | 0.40 | 0.76 | 19 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O54990
- Elsewhere: UniProt O54990 · AlphaFold DB O54990
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