Research workbench
AlphaFold monomer V2.0 prediction for DNA polymerase iota (Q6R3M4)
Analyse AlphaFold monomer V2.0 prediction for DNA polymerase iota (Q6R3M4) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q6R3M4
- Type
- protein
- Length
- 717 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
- Molecule
- DNA polymerase iota
- UniProt
- Q6R3M4
- Pockets
- 4 · best druggability 0.53
Structure
1 distinct chain · 31% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA polymerase iota | protein | 717 | 31% helix, 12% strand | Q6R3M4 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 329 | 0.53 | 0.74 | 40 | empty |
| 2 | 121 | 0.38 | 0.73 | 14 | empty |
| 3 | 102 | 0.37 | 0.74 | 17 | empty |
| 4 | 77 | 0.29 | 0.72 | 17 | empty |
Compared structures
- 3AI4 · Crystal structure of yeast enhanced green fluorescent protein - mouse polymerase iota… · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 3AI4 · Crystal structure of yeast enhanced green fluorescent protein - mouse polymerase iota… · an experimental structure of the same protein · chain A against A, TM-score 0.13
- 2KWU · Solution Structure of UBM2 of murine Polymerase iota in Complex with Ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2KWU · Solution structure of UBM2 of murine polymerase iota in complex with ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.05
- 2KWV · Solution Structure of UBM1 of murine Polymerase iota in Complex with Ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.04
- 2KWV · Solution structure of UBM1 of murine polymerase iota in complex with ubiquitin · an experimental structure of the same protein · chain A against A, TM-score 0.04
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6R3M4
- Elsewhere: UniProt Q6R3M4 · AlphaFold DB Q6R3M4
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