Research workbench
AlphaFold monomer V2.0 prediction for dolichyl-phosphate-mannose-- protein mannosyltransferase 2 (P31382)
Analyse AlphaFold monomer V2.0 prediction for dolichyl-phosphate-mannose-- protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P31382
- Type
- protein
- Length
- 759 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x403EcfA800ce17640bdC169169720B7Bf7e06A2b
- Molecule
- Dolichyl-phosphate-mannose--protein mannosyltransferase 2
- UniProt
- P31382
- Pockets
- 9 · best druggability 0.66
Structure
1 distinct chain · 48% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 | protein | 759 | 48% helix, 13% strand | P31382 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 294 | 0.66 | 0.81 | 40 | empty |
| 2 | 350 | 0.63 | 0.79 | 53 | empty |
| 3 | 199 | 0.49 | 0.75 | 26 | empty |
| 4 | 210 | 0.46 | 0.74 | 24 | empty |
| 5 | 114 | 0.41 | 0.75 | 22 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 6P2R · Structure of S. cerevisiae protein O-mannosyltransferase PMT1-PMT2 complex bound to the… · an experimental structure of the same protein · chain A against B, TM-score 0.86
- 6P2R · Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the… · an experimental structure of the same protein · chain A against B, TM-score 0.86
- 6P25 · Structure of S. cerevisiae protein O-mannosyltransferase PMT1-PMT2 complex bound to the… · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 6P25 · Structure of S. cerevisiae protein O-mannosyltransferase Pmt1-Pmt2 complex bound to the… · an experimental structure of the same protein · chain A against B, TM-score 0.85
- 6P28 · Crystal structure of the mir domain (aa 337-532) of the S. cerevisiae mannosyltransferase… · an experimental structure of the same protein · chain A against A, TM-score 0.25
- 6P28 · Crystal structure of the MIR domain (aa 337-532) of the S. cerevisiae mannosyltransferase… · an experimental structure of the same protein · chain A against A, TM-score 0.25
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31382
- Elsewhere: UniProt P31382 · AlphaFold DB P31382
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