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AlphaFold monomer V2.0 prediction for 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (Q9NST1)

Analyse AlphaFold monomer V2.0 prediction for 1-acylglycerol-3-phosphate… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9NST1
Type
protein
Length
481 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x2FCae8136DBc761f6F9310fF638e0F8Ad73E2B9d
Molecule
1-acylglycerol-3-phosphate O-acyltransferase PNPLA3
UniProt
Q9NST1
Pockets
10 · best druggability 0.82

Structure

1 distinct chain · 46% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A1-acylglycerol-3-phosphate O-acyltransferase PNPLA3protein48146% helix, 9% strandQ9NST1

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14250.820.8960empty
23420.600.7729empty
32710.590.7828empty
41280.560.8217empty
51190.450.7717empty

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