Research workbench

AlphaFold monomer V2.0 prediction for pleckstrin (Q9JHK5)

Analyse AlphaFold monomer V2.0 prediction for pleckstrin (Q9JHK5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q9JHK5
Type: protein
Length: 350 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7A88760075f28CD17Ed2Ff297A0605400536f5e9
Molecule: Pleckstrin
UniProt: Q9JHK5
Pockets: 6 · best druggability 0.72

Structure

1 distinct chain · 23% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pleckstrin	protein	350	23% helix, 31% strand	Q9JHK5

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	318	0.72	0.84	35	empty
2	224	0.56	0.78	26	empty
3	262	0.51	0.75	26	empty
4	193	0.48	0.75	21	empty
5	156	0.45	0.76	25	empty

Compared structures

1UHW · Solution structure of the DEP domain of mouse pleckstrin · an experimental structure of the same protein · chain A against A, TM-score 0.29
1UHW · Solution structure of the dep domain of mouse pleckstrin · an experimental structure of the same protein · chain A against A, TM-score 0.29

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9JHK5
Elsewhere: UniProt Q9JHK5 · AlphaFold DB Q9JHK5

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