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AlphaFold monomer V2.0 prediction for junction plakoglobin (P14923)

Analyse AlphaFold monomer V2.0 prediction for junction plakoglobin (P14923) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P14923
Type: protein
Length: 745 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xf4ED13986579E8e227b3ED6c02276c648754EC27
Molecule: Junction plakoglobin
UniProt: P14923
Pockets: 3 · best druggability 0.70

Structure

1 distinct chain · 63% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Junction plakoglobin	protein	745	63% helix, 0% strand	P14923

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	361	0.70	0.82	62	empty
2	515	0.68	0.78	41	empty
3	316	0.56	0.75	33	empty

Compared structures

3IFQ · Interction of plakoglobin and beta-catenin with desmosomal cadherins · an experimental structure of the same protein · chain A against A, TM-score 0.72
3IFQ · Interction of plakoglobin and beta-catenin with desmosomal cadherins · an experimental structure of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P14923
Elsewhere: UniProt P14923 · AlphaFold DB P14923

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