Research workbench
AlphaFold monomer V2.0 prediction for pleckstrin homology domain- containing family H member 2 (Q8IVE3)
Analyse AlphaFold monomer V2.0 prediction for pleckstrin homology domain- containing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8IVE3
- Type
- protein
- Length
- 1,493 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x9F605311B7e26e76340423EfAfbE5e2EFc7A0b7C
- Molecule
- Pleckstrin homology domain-containing family H member 2
- UniProt
- Q8IVE3
- Pockets
- 15 · best druggability 0.75
Structure
1 distinct chain · 31% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pleckstrin homology domain-containing family H member 2 | protein | 1493 | 31% helix, 11% strand | Q8IVE3 |
Pockets
15 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 805 | 0.75 | 0.80 | 81 | empty |
| 2 | 428 | 0.66 | 0.79 | 45 | empty |
| 3 | 445 | 0.62 | 0.76 | 41 | empty |
| 4 | 220 | 0.51 | 0.76 | 24 | empty |
| 5 | 111 | 0.43 | 0.77 | 21 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8IVE3
- Elsewhere: UniProt Q8IVE3 · AlphaFold DB Q8IVE3
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