AlphaFold monomer V2.0 prediction for periplasmic [nife] hydrogenase large subunit (P18188)

Structure

1 distinct chain · 46% helix, 15% strand (DSSP).

Pockets

4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

• 4UQP · High-resolution structure of the D. fructosovorans NiFe-hydrogenase L122A mutant after… · an experimental structure of the same protein · chain A against R, TM-score 0.97
• 4UQP · High-resolution structure of the D. fructosovorans nife-hydrogenase L122A mutant after… · an experimental structure of the same protein · chain A against R, TM-score 0.97
• 4UEW · Structure of H2-treated anaerobically purified D. fructosovorans nife- hydrogenase · an experimental structure of the same protein · chain A against R, TM-score 0.96
• 4UEW · Structure of H2-treated anaerobically purified D. fructosovorans NiFe- hydrogenase · an experimental structure of the same protein · chain A against R, TM-score 0.96
• 3CUR · Structure of a double methionine mutant of NI-FE hydrogenase · an experimental structure of the same protein · chain A against H, TM-score 0.96
• 3CUR · Structure of a double methionine mutant of ni-fe hydrogenase · an experimental structure of the same protein · chain A against H, TM-score 0.96
• 3H3X · Structure of the V74M large subunit mutant of ni-fe hydrogenase in an oxidized state · an experimental structure of the same protein · chain A against R, TM-score 0.96
• 3H3X · Structure of the V74M large subunit mutant of NI-FE hydrogenase in an oxidized state · an experimental structure of the same protein · chain A against R, TM-score 0.96
• 3CUS · Structure of a double ILE/PHE mutant of NI-FE hydrogenase refined at 2.2 angstrom… · an experimental structure of the same protein · chain A against R, TM-score 0.96
• 3CUS · Structure of a double ILE/PHE mutant of ni-fe hydrogenase refined at 2.2 ångström… · an experimental structure of the same protein · chain A against R, TM-score 0.96
• 4UPE · Structure of the unready Ni-A state of the S499C mutant of D. fructosovorans… · an experimental structure of the same protein · chain A against Q, TM-score 0.96
• 4UPE · Structure of the unready ni-a state of the S499C mutant of D. fructosovorans… · an experimental structure of the same protein · chain A against Q, TM-score 0.96

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P18188
• Elsewhere: UniProt P18188 · AlphaFold DB P18188