Research workbench
AlphaFold monomer V2.0 prediction for pH domain leucine-rich repeat- containing protein phosphatase 1 (O60346)
Analyse AlphaFold monomer V2.0 prediction for pH domain leucine-rich repeat- containing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O60346
- Type
- protein
- Length
- 1,717 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x527Fc9Ea796aC165D96B0eDa7256bB7d212B69Df
- Molecule
- PH domain leucine-rich repeat-containing protein phosphatase 1
- UniProt
- O60346
- Pockets
- 15 · best druggability 0.82
Structure
1 distinct chain · 14% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | PH domain leucine-rich repeat-containing protein phosphatase 1 | protein | 1717 | 14% helix, 14% strand | O60346 |
Pockets
15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1010 | 0.82 | 0.83 | 90 | empty |
| 2 | 465 | 0.80 | 0.88 | 64 | empty |
| 3 | 197 | 0.71 | 0.88 | 29 | empty |
| 4 | 534 | 0.70 | 0.80 | 53 | empty |
| 5 | 109 | 0.66 | 0.90 | 22 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60346
- Elsewhere: UniProt O60346 · AlphaFold DB O60346
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