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AlphaFold monomer V2.0 prediction for DNA polymerase sliding clamp (O73947)

Analyse AlphaFold monomer V2.0 prediction for DNA polymerase sliding clamp (O73947) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
O73947
Type
protein
Length
249 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x80D2ac0F5e3268bC5C1d28BBAA07E3169BB02b79
Molecule
DNA polymerase sliding clamp
UniProt
O73947
Pockets
1 · best druggability 0.32

Structure

1 distinct chain · 16% helix, 47% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA polymerase sliding clampprotein24916% helix, 47% strandO73947

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1640.320.7615empty

Compared structures

  • 3A2F · Crystal Structure of Pyrococcus furiosus DNA polymerase/PCNA monomer mutant complex · an experimental structure of the same protein · chain A against B, TM-score 0.96
  • 3A2F · Crystal structure of pyrococcus furiosus DNA POLYMERASE/PCNA monomer mutant complex · an experimental structure of the same protein · chain A against B, TM-score 0.96
  • 1IZ4 · Pyrococcus furiosus PCNA mutant (MET73LEU/ASP143ALA): tetragonal form · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 1IZ4 · Pyrococcus furiosus PCNA mutant (Met73Leu/Asp143Ala): tetragonal form · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 1ISQ · Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 1ISQ · Pyrococcus furiosus PCNA complexed with rfcl pip-box peptide · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 5AUJ · Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) semet derivative · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 5AUJ · Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative · an experimental structure of the same protein · chain A against A, TM-score 0.94
  • 1GE8 · Proliferating cell nuclear antigen (PCNA) homolog from pyrococcus furiosus · an experimental structure of the same protein · chain A against A, TM-score 0.93
  • 1GE8 · Proliferating cell nuclear antigen (PCNA) homolog from pyrococcus furiosus · an experimental structure of the same protein · chain A against A, TM-score 0.93
  • 1IZ5 · Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 1IZ5 · Pyrococcus furiosus PCNA mutant (MET73LEU, ASP143ALA, ASP147ALA): orthorhombic form · an experimental structure of the same protein · chain A against A, TM-score 0.92

Analyse

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