Research workbench

AlphaFold monomer V2.0 prediction for MAP kinase kinase PBS2 (P08018)

Analyse AlphaFold monomer V2.0 prediction for MAP kinase kinase PBS2 (P08018) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: P08018
Type: protein
Length: 668 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xaF0Dee25ddf5E46fC5F06F9c967adD3be668e3c6
Molecule: MAP kinase kinase PBS2
UniProt: P08018
Pockets: 6 · best druggability 0.74

Structure

1 distinct chain · 25% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	MAP kinase kinase PBS2	protein	668	25% helix, 10% strand	P08018

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	716	0.74	0.80	73	empty
2	612	0.69	0.78	42	empty
3	184	0.52	0.78	30	empty
4	114	0.51	0.81	19	empty
5	129	0.45	0.77	23	empty

Compared structures

2VKN · Yeast SHO1 SH3 domain complexed with a peptide from PBS2 · an experimental structure of the same protein · chain A against C, TM-score 0.01
2VKN · Yeast SHO1 SH3 domain complexed with a peptide from PBS2 · an experimental structure of the same protein · chain A against C, TM-score 0.01

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08018
Elsewhere: UniProt P08018 · AlphaFold DB P08018

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.