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AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit a (Q8CSN8)

Analyse AlphaFold monomer V2.0 prediction for DNA topoisomerase 4 subunit a (Q8CSN8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8CSN8
Type
protein
Length
800 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x52Af21eE47b292Ffe1FB3cF21692083152a4766A
Molecule
DNA topoisomerase 4 subunit a
UniProt
Q8CSN8
Pockets
6 · best druggability 0.69

Structure

1 distinct chain · 34% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA topoisomerase 4 subunit aprotein80034% helix, 26% strandQ8CSN8

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17560.690.7652empty
2980.520.8317empty
31760.480.7732empty
4620.430.8113empty
51300.430.7618empty

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