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AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit M (P0AFE8)

Analyse AlphaFold monomer V2.0 prediction for NADH-quinone oxidoreductase subunit M… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P0AFE8
Type
protein
Length
509 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
NADH-quinone oxidoreductase subunit M
UniProt
P0AFE8
Pockets
2 · best druggability 0.57

Structure

1 distinct chain · 75% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANADH-quinone oxidoreductase subunit Mprotein50975% helix, 3% strandP0AFE8

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11530.570.8116empty
2570.320.7512empty

Compared structures

  • 7NYV · Respiratory complex I from Escherichia coli - conformation 3 · an experimental structure of the same protein · chain A against M, TM-score 0.96
  • 7NYV · Respiratory complex I from escherichia COLI - conformation 3 · an experimental structure of the same protein · chain A against M, TM-score 0.96
  • 7NYU · Respiratory complex I from Escherichia coli - conformation 2 · an experimental structure of the same protein · chain A against M, TM-score 0.96
  • 7NYU · Respiratory complex I from escherichia COLI - conformation 2 · an experimental structure of the same protein · chain A against M, TM-score 0.96
  • 7NYH · Respiratory complex I from Escherichia coli - focused refinement of membrane arm · an experimental structure of the same protein · chain A against M, TM-score 0.96
  • 7NYH · Respiratory complex I from escherichia COLI - focused refinement of membrane arm · an experimental structure of the same protein · chain A against M, TM-score 0.96
  • 7NYR · Respiratory complex I from Escherichia coli - conformation 1 · an experimental structure of the same protein · chain A against M, TM-score 0.96
  • 7NYR · Respiratory complex I from escherichia COLI - conformation 1 · an experimental structure of the same protein · chain A against M, TM-score 0.96

Analyse

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