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AlphaFold monomer V2.0 prediction for GDP-mannose pyrophosphatase (P37128)

Analyse AlphaFold monomer V2.0 prediction for GDP-mannose pyrophosphatase (P37128) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P37128
Type
protein
Length
191 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x52dd39a1F0b0b49aB790E19FD5d5b8d2eb36C77b
Molecule
GDP-mannose pyrophosphatase
UniProt
P37128
Pockets
1 · best druggability 0.54

Structure

1 distinct chain · 22% helix, 42% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AGDP-mannose pyrophosphataseprotein19122% helix, 42% strandP37128

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13110.540.7540empty

Compared structures

  • 3O69 · Structure of the E100A E.COLI GDP-mannose hydrolase (yffh) in complex with mg++ · an experimental structure of the same protein · chain A against B, TM-score 0.99
  • 3O69 · Structure of the E100A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++ · an experimental structure of the same protein · chain A against B, TM-score 0.99
  • 3O6Z · Structure of the D152A E.COLI GDP-mannose hydrolase (yffh) in complex with mg++ · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 3O6Z · Structure of the D152A E.coli GDP-mannose hydrolase (yffh) in complex with Mg++ · an experimental structure of the same protein · chain A against B, TM-score 0.98
  • 3O61 · Structure of the E100A E.COLI GDP-mannose hydrolase (yffh) in complex with GDP-mannose… · an experimental structure of the same protein · chain A against D, TM-score 0.98
  • 3O61 · Structure of the E100A E.coli GDP-mannose hydrolase (yffh) in complex with GDP-mannose… · an experimental structure of the same protein · chain A against D, TM-score 0.98

Analyse

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