Research workbench
AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 1 (O78747)
Analyse AlphaFold monomer V2.0 prediction for NADH-ubiquinone oxidoreductase chain 1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O78747
- Type
- protein
- Length
- 318 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5c4adF1416281C09AE8eE1cbb80fF7e44cE86F97
- Molecule
- NADH-ubiquinone oxidoreductase chain 1
- UniProt
- O78747
- Pockets
- 4 · best druggability 0.78
Structure
1 distinct chain · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH-ubiquinone oxidoreductase chain 1 | protein | 318 | 69% helix, 0% strand | O78747 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 117 | 0.78 | 0.97 | 29 | empty |
| 2 | 201 | 0.56 | 0.79 | 23 | empty |
| 3 | 194 | 0.51 | 0.76 | 24 | empty |
| 4 | 82 | 0.41 | 0.77 | 13 | empty |
Compared structures
- 6ZKO · Native complex I, closed · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 6ZKK · Complex I inhibited by rotenone, closed · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 6ZKG · Complex I with NADH, closed · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 7ZDM · Complex I from Ovis aries at pH5.5, Closed state · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 6ZKC · Complex I during turnover, closed · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 6ZKC · Complex I during turnover, closed · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 6ZKB · Membrane domain of closed complex I during turnover · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 6ZKB · Membrane domain of closed complex I during turnover · an experimental structure of the same protein · chain A against H, TM-score 0.98
- 6ZKN · Complex I inhibited by rotenone, OPEN3 · an experimental structure of the same protein · chain A against H, TM-score 0.97
- 6ZKM · Complex I inhibited by rotenone, OPEN2 · an experimental structure of the same protein · chain A against H, TM-score 0.97
- 6ZKL · Complex I inhibited by rotenone, OPEN1 · an experimental structure of the same protein · chain A against H, TM-score 0.97
- 6ZKL · Complex I inhibited by rote , open1 · an experimental structure of the same protein · chain A against H, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O78747
- Elsewhere: UniProt O78747 · AlphaFold DB O78747
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.