Research workbench
AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase NSD2 (Q8BVE8)
Analyse AlphaFold monomer V2.0 prediction for histone-lysine N-methyltransferase NSD2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8BVE8
- Type
- protein
- Length
- 1,365 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x08f1B0edc8474cb3B0f88330111598d367318E80
- Molecule
- Histone-lysine N-methyltransferase NSD2
- UniProt
- Q8BVE8
- Pockets
- 13 · best druggability 0.77
Structure
1 distinct chain · 16% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Histone-lysine N-methyltransferase NSD2 | protein | 1365 | 16% helix, 12% strand | Q8BVE8 |
Pockets
13 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 855 | 0.77 | 0.80 | 71 | empty |
| 2 | 892 | 0.76 | 0.79 | 88 | empty |
| 3 | 350 | 0.71 | 0.84 | 37 | empty |
| 4 | 310 | 0.67 | 0.82 | 40 | empty |
| 5 | 165 | 0.55 | 0.80 | 33 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8BVE8
- Elsewhere: UniProt Q8BVE8 · AlphaFold DB Q8BVE8
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