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AlphaFold monomer V2.0 prediction for nuclear exosome regulator NRDE2 (Q80XC6)

Analyse AlphaFold monomer V2.0 prediction for nuclear exosome regulator NRDE2 (Q80XC6) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q80XC6
Type
protein
Length
1,172 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
Molecule
Nuclear exosome regulator NRDE2
UniProt
Q80XC6
Pockets
11 · best druggability 0.75

Structure

1 distinct chain · 55% helix, 1% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANuclear exosome regulator NRDE2protein117255% helix, 1% strandQ80XC6

Pockets

11 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11210.750.9530empty
29960.750.7869empty
38120.710.7753empty
49430.710.7688empty
54520.710.8157empty

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