Research workbench
AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 1 group I member 2 (O75469)
Analyse AlphaFold monomer V2.0 prediction for nuclear receptor subfamily 1 group I… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O75469
- Type
- protein
- Length
- 434 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xCf85BFe421DF41E218886F0b64e33F2b5FDB0e91
- Molecule
- Nuclear receptor subfamily 1 group I member 2
- UniProt
- O75469
- Pockets
- 2 · best druggability 0.86
Structure
1 distinct chain · 49% helix, 7% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nuclear receptor subfamily 1 group I member 2 | protein | 434 | 49% helix, 7% strand | O75469 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 344 | 0.86 | 0.95 | 40 | empty |
| 2 | 63 | 0.27 | 0.73 | 14 | empty |
Compared structures
- 6TFI · Pxr in complex with thrombin inhibitor compound 17 · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 6TFI · Pxr in complex with thrombin inhibitor compound 17 · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 2O9I · Crystal Structure of the Human Pregnane X Receptor LBD in complex with an SRC-1… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 2O9I · Crystal structure of the human pregnane X receptor lbd in complex with an src-1… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 6HTY · Pxr in complex with P2X4 inhibitor compound 25 · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 6HTY · PXR in complex with P2X4 inhibitor compound 25 · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 4X1G · Crystal structure of the hpxr-lbd in complex with the synthetic estrogen… · an experimental structure of the same protein · chain A against A, TM-score 0.64
- 4X1G · Crystal structure of the hPXR-LBD in complex with the synthetic estrogen… · an experimental structure of the same protein · chain A against A, TM-score 0.64
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75469
- Elsewhere: UniProt O75469 · AlphaFold DB O75469
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