Research workbench
AlphaFold monomer V2.0 prediction for bile acid receptor (Q62735)
Analyse AlphaFold monomer V2.0 prediction for bile acid receptor (Q62735) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q62735
- Type
- protein
- Length
- 469 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x13E88C248c9e8FD361F590BE0a618ae231254269
- Molecule
- Bile acid receptor
- UniProt
- Q62735
- Pockets
- 3 · best druggability 0.80
Structure
1 distinct chain · 46% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Bile acid receptor | protein | 469 | 46% helix, 2% strand | Q62735 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 237 | 0.80 | 0.92 | 45 | empty |
| 2 | 176 | 0.46 | 0.75 | 22 | empty |
| 3 | 130 | 0.41 | 0.74 | 19 | empty |
Compared structures
- 1OSV · Structural basis for bile acid binding and activation of the nuclear receptor fxr · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 1OSV · Structural basis for bile acid binding and activation of the nuclear receptor fxr · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 1OT7 · Structural Basis for 3-deoxy-CDCA Binding and Activation of FXR · an experimental structure of the same protein · chain A against A, TM-score 0.46
- 1OT7 · Structural basis for 3-deoxy-cdca binding and activation of fxr · an experimental structure of the same protein · chain A against A, TM-score 0.46
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q62735
- Elsewhere: UniProt Q62735 · AlphaFold DB Q62735
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