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AlphaFold monomer V2.0 prediction for ribosome biogenesis protein NOP53 (Q9NZM5)

Analyse AlphaFold monomer V2.0 prediction for ribosome biogenesis protein NOP53 (Q9NZM5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9NZM5
Type
protein
Length
478 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5F44328A27457eA9cB313ce81Efc1023D2D1BB41
Molecule
Ribosome biogenesis protein NOP53
UniProt
Q9NZM5
Pockets
2 · best druggability 0.43

Structure

1 distinct chain · 42% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARibosome biogenesis protein NOP53protein47842% helix, 0% strandQ9NZM5

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11610.430.7528empty
2850.400.7816empty

Compared structures

  • 8FL2 · Human nuclear pre-60S ribosomal subunit (State I1) · an experimental structure of the same protein · chain A against NL, TM-score 0.35
  • 8FL3 · Human nuclear pre-60S ribosomal subunit (State I2) · an experimental structure of the same protein · chain A against NL, TM-score 0.35
  • 8FL4 · Human nuclear pre-60S ribosomal subunit (State I3) · an experimental structure of the same protein · chain A against NL, TM-score 0.35
  • 8FLD · Human nuclear pre-60S ribosomal subunit (State L1) · an experimental structure of the same protein · chain A against NL, TM-score 0.35
  • 8FLA · Human nuclear pre-60S ribosomal subunit (State K1) · an experimental structure of the same protein · chain A against NL, TM-score 0.35
  • 8FL6 · Human nuclear pre-60S ribosomal subunit (State J1) · an experimental structure of the same protein · chain A against NL, TM-score 0.34
  • 8FKZ · Human nucleolar pre-60S ribosomal subunit (State G) · an experimental structure of the same protein · chain A against NL, TM-score 0.34
  • 8FLE · Human nuclear pre-60S ribosomal subunit (State L2) · an experimental structure of the same protein · chain A against NL, TM-score 0.34
  • 8INF · human nuclear pre-60S ribosomal particle - State F' · an experimental structure of the same protein · chain A against w, TM-score 0.34
  • 8FL7 · Human nuclear pre-60S ribosomal subunit (State J2) · an experimental structure of the same protein · chain A against NL, TM-score 0.34
  • 8FLB · Human nuclear pre-60S ribosomal subunit (State K2) · an experimental structure of the same protein · chain A against NL, TM-score 0.34
  • 8INE · human nuclear pre-60S ribosomal particle - State G' · an experimental structure of the same protein · chain A against w, TM-score 0.34

Analyse

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