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AlphaFold monomer V2.0 prediction for neuroligin-2 (Q62888)

Analyse AlphaFold monomer V2.0 prediction for neuroligin-2 (Q62888) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q62888
Type
protein
Length
836 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xD6405a3FdE14968240b76e4f9AE6d0CA1919f533
Molecule
Neuroligin-2
UniProt
Q62888
Pockets
8 · best druggability 0.68

Structure

1 distinct chain · 31% helix, 10% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ANeuroligin-2protein83631% helix, 10% strandQ62888

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12380.680.8544empty
21920.640.8431empty
33390.630.7939empty
43010.570.7734empty
51910.550.7922empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 5V5V · Complex of NLGN2 with MDGA1 Ig1-Ig2 · an experimental structure of the same protein · chain A against A, TM-score 0.62
  • 5V5V · Complex of NLGN2 with MDGA1 IG1-IG2 · an experimental structure of the same protein · chain A against A, TM-score 0.62

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