Research workbench
AlphaFold monomer V2.0 prediction for neogenin (P97798)
Analyse AlphaFold monomer V2.0 prediction for neogenin (P97798) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P97798
- Type
- protein
- Length
- 1,493 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
- Molecule
- Neogenin
- UniProt
- P97798
- Pockets
- 6 · best druggability 0.59
Structure
1 distinct chain · 2% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neogenin | protein | 1493 | 2% helix, 33% strand | P97798 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 390 | 0.59 | 0.76 | 45 | empty |
| 2 | 238 | 0.50 | 0.75 | 31 | empty |
| 3 | 78 | 0.36 | 0.76 | 17 | empty |
| 4 | 76 | 0.35 | 0.76 | 19 | empty |
| 5 | 62 | 0.31 | 0.75 | 20 | empty |
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 4BQ9 · Crystal structure of the FN5 and FN6 domains of NEO1, form 1 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 4BQ9 · Crystal structure of the FN5 and FN6 domains of NEO1, form 1 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 4BQ6 · Crystal structure of the rgmb-NEO1 complex form 1 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 4BQ6 · Crystal structure of the RGMB-NEO1 complex form 1 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 6Z3M · Repulsive guidance molecule B (rgmb) in complex with growth differentiation factor 5… · an experimental structure of the same protein · chain A against E, TM-score 0.12
- 4BQB · Crystal structure of the FN5 and FN6 domains of NEO1, form 2 · an experimental structure of the same protein · chain A against D, TM-score 0.12
- 4BQB · Crystal structure of the FN5 and FN6 domains of NEO1, form 2 · an experimental structure of the same protein · chain A against D, TM-score 0.12
- 4BQ7 · Crystal structure of the rgmb-NEO1 complex form 2 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 4BQ7 · Crystal structure of the RGMB-Neo1 complex form 2 · an experimental structure of the same protein · chain A against A, TM-score 0.12
- 4BQC · Crystal structure of the FN5 and FN6 domains of NEO1 bound to SOS · an experimental structure of the same protein · chain A against A, TM-score 0.12
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P97798
- Elsewhere: UniProt P97798 · AlphaFold DB P97798
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