Research workbench
AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (P17694)
Analyse AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone]… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P17694
- Type
- protein
- Length
- 463 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x5BeA89782341f98147F2D811B063F91F0aE7D7bF
- Molecule
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial
- UniProt
- P17694
- Pockets
- 3 · best druggability 0.39
Structure
1 distinct chain · 45% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | protein | 463 | 45% helix, 11% strand | P17694 |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 50 | 0.39 | 0.82 | 15 | empty |
| 2 | 71 | 0.33 | 0.75 | 16 | empty |
| 3 | 60 | 0.30 | 0.75 | 13 | empty |
Compared structures
- 7QSM · Bovine complex I in lipid nanodisc, deactive-ligand (composite) · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7QSM · Bovine complex I in lipid nanodisc, Deactive-ligand (composite) · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 8Q0M · Outward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7QSK · Bovine complex I in lipid nanodisc, active-Q10 · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7QSK · Bovine complex I in lipid nanodisc, Active-Q10 · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7QSL · Bovine complex I in lipid nanodisc, active-apo · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7QSL · Bovine complex I in lipid nanodisc, Active-apo · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 8Q0A · Inward-facing, closed proteoliposome complex I at 3.1 A. Initially purified in DDM. · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 8Q48 · Outward-facing, closed proteoliposome complex I at 2.5 A. Initially purified in LMNG. · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7R42 · Bovine complex I in the presence of IM1761092, active class ii (Composite map) · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7QSD · Bovine complex I in the active state at 3.1 A · an experimental structure of the same protein · chain A against D, TM-score 0.91
- 7QSD · Bovine complex I in the active state at 3.1 a · an experimental structure of the same protein · chain A against D, TM-score 0.91
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17694
- Elsewhere: UniProt P17694 · AlphaFold DB P17694
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