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AlphaFold monomer V2.0 prediction for rotenone-insensitive NADH- ubiquinone oxidoreductase, mitochondrial (P32340)

Analyse AlphaFold monomer V2.0 prediction for rotenone-insensitive NADH- ubiquinone… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P32340
Type
protein
Length
513 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x29881a02D129107C6a36da89fe03D8284a85EFE1
Molecule
Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial
UniProt
P32340
Pockets
5 · best druggability 0.80

Structure

1 distinct chain · 31% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrialprotein51331% helix, 25% strandP32340

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
110300.800.82103empty
2770.420.8018empty
3550.400.8219empty
4710.400.7917empty
5600.290.7414empty

Compared structures

  • 4G6H · Crystal structure of ndh with NADH · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4G6H · Crystal structure of NDH with NADH · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4G73 · Crystal structure of NDH with NADH and Qui · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4G73 · Crystal structure of ndh with NADH and quinone · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4G74 · Crystal structure of ndh with quinone · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4G74 · Crystal structure of NDH with Qui · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4G6G · Crystal structure of ndh with trt · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4G6G · Crystal structure of NDH with TRT · an experimental structure of the same protein · chain A against A, TM-score 0.91
  • 4GAP · Structure of the Ndi1 protein from Saccharomyces cerevisiae in complex with NAD+ · an experimental structure of the same protein · chain A against A, TM-score 0.90
  • 4GAP · Structure of the NDI1 protein from saccharomyces cerevisiae in complex with NAD+ · an experimental structure of the same protein · chain A against A, TM-score 0.90
  • 4G9K · Structure of the Ndi1 protein from Saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.90
  • 4G9K · Structure of the NDI1 protein from saccharomyces cerevisiae · an experimental structure of the same protein · chain A against A, TM-score 0.90

Analyse

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