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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q5X4B2)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein muts (Q5X4B2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q5X4B2
Type
protein
Length
846 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xA4D9B5300039B74C1Cd502B506a822364e6BC90A
Molecule
DNA mismatch repair protein muts
UniProt
Q5X4B2
Pockets
10 · best druggability 0.72

Structure

1 distinct chain · 48% helix, 19% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein mutsprotein84648% helix, 19% strandQ5X4B2

Pockets

10 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11160.720.9323empty
24390.680.8047empty
34380.640.7733empty
44810.630.7649empty
51280.450.7721empty

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