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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8UHI3)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein mutl (Q8UHI3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8UHI3
Type
protein
Length
606 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
Molecule
DNA mismatch repair protein mutl
UniProt
Q8UHI3
Pockets
6 · best druggability 0.72

Structure

1 distinct chain · 37% helix, 22% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein mutlprotein60637% helix, 22% strandQ8UHI3

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12470.720.8732empty
25320.630.7658empty
31870.550.7936empty
41630.520.7919empty
51280.460.7737empty

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