Research workbench
AlphaFold monomer V2.0 prediction for muscle, skeletal receptor tyrosine-protein kinase (O15146)
Analyse AlphaFold monomer V2.0 prediction for muscle, skeletal receptor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O15146
- Type
- protein
- Length
- 869 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x78Cc7f9BF18AF8279e492D45EE7Fe9d7cC6f6D07
- Molecule
- Muscle, skeletal receptor tyrosine-protein kinase
- UniProt
- O15146
- Pockets
- 10 · best druggability 0.73
Structure
1 distinct chain · 26% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Muscle, skeletal receptor tyrosine-protein kinase | protein | 869 | 26% helix, 29% strand | O15146 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 260 | 0.73 | 0.87 | 31 | empty |
| 2 | 390 | 0.73 | 0.83 | 35 | empty |
| 3 | 734 | 0.68 | 0.76 | 69 | empty |
| 4 | 58 | 0.48 | 0.85 | 17 | empty |
| 5 | 165 | 0.47 | 0.76 | 33 | empty |
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 8S9P · 1:1:1 agrin/LRP4/MuSK complex · an experimental structure of the same protein · chain A against C, TM-score 0.11
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15146
- Elsewhere: UniProt O15146 · AlphaFold DB O15146
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.