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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (Q4P6I8)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (Q4P6I8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q4P6I8
Type
protein
Length
1,154 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x4d07E6a23DeB6B95bd9b90EcB67368b7e8D3B77e
Molecule
DNA mismatch repair protein MSH3
UniProt
Q4P6I8
Pockets
10 · best druggability 0.85

Structure

1 distinct chain · 39% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein MSH3protein115439% helix, 14% strandQ4P6I8

Pockets

10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
110530.850.8697empty
22540.660.8348empty
3690.580.8916empty
43710.560.7543empty
53420.530.7334empty

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