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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (A4R0R0)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (A4R0R0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A4R0R0
Type
protein
Length
1,151 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x8a24CBa3fbFCBbB9686CfD21aB7D75cD5a37f2D0
Molecule
DNA mismatch repair protein MSH3
UniProt
A4R0R0
Pockets
7 · best druggability 0.76

Structure

1 distinct chain · 40% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein MSH3protein115140% helix, 14% strandA4R0R0

Pockets

7 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17760.760.8179empty
24510.740.8467empty
34590.700.8145empty
43330.640.7936empty
54120.590.7549empty

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