Research workbench
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (Q1ZXH0)
Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (Q1ZXH0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q1ZXH0
- Type
- protein
- Length
- 1,428 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x429aA010A80A47FF4a2777bB34A2bba144d19df2
- Molecule
- DNA mismatch repair protein MSH3
- UniProt
- Q1ZXH0
- Pockets
- 13 · best druggability 0.83
Structure
1 distinct chain · 35% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein MSH3 | protein | 1428 | 35% helix, 11% strand | Q1ZXH0 |
Pockets
13 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1150 | 0.83 | 0.84 | 115 | empty |
| 2 | 404 | 0.71 | 0.82 | 50 | empty |
| 3 | 533 | 0.69 | 0.79 | 49 | empty |
| 4 | 632 | 0.65 | 0.75 | 48 | empty |
| 5 | 261 | 0.58 | 0.78 | 28 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1ZXH0
- Elsewhere: UniProt Q1ZXH0 · AlphaFold DB Q1ZXH0
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