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AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (A6R7S1)

Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH3 (A6R7S1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A6R7S1
Type
protein
Length
1,166 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xbDA05C32aD6eE153C8C5A78dfa48d7Ba25694fea
Molecule
DNA mismatch repair protein MSH3
UniProt
A6R7S1
Pockets
9 · best druggability 0.78

Structure

1 distinct chain · 40% helix, 14% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA mismatch repair protein MSH3protein116640% helix, 14% strandA6R7S1

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15970.780.8464empty
28710.770.8084empty
31610.540.8021empty
43400.540.7438empty
52470.500.7533empty

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