Research workbench
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH2 (O74773)
Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH2 (O74773) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O74773
- Type
- protein
- Length
- 982 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x025f3b1a898b05AD2731bE6Ab72687b5920c4A3F
- Molecule
- DNA mismatch repair protein MSH2
- UniProt
- O74773
- Pockets
- 13 · best druggability 0.86
Structure
1 distinct chain · 49% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein MSH2 | protein | 982 | 49% helix, 18% strand | O74773 |
Pockets
13 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1189 | 0.86 | 0.86 | 111 | empty |
| 2 | 408 | 0.63 | 0.78 | 30 | empty |
| 3 | 184 | 0.48 | 0.76 | 25 | empty |
| 4 | 98 | 0.44 | 0.79 | 28 | empty |
| 5 | 62 | 0.43 | 0.82 | 13 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74773
- Elsewhere: UniProt O74773 · AlphaFold DB O74773
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