Research workbench
AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH2 (Q553L4)
Analyse AlphaFold monomer V2.0 prediction for DNA mismatch repair protein MSH2 (Q553L4) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q553L4
- Type
- protein
- Length
- 937 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x24b6633C8ABa741dB6572E7cDdf0Af3176c8A10F
- Molecule
- DNA mismatch repair protein MSH2
- UniProt
- Q553L4
- Pockets
- 10 · best druggability 0.82
Structure
1 distinct chain · 47% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA mismatch repair protein MSH2 | protein | 937 | 47% helix, 18% strand | Q553L4 |
Pockets
10 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1182 | 0.82 | 0.83 | 107 | empty |
| 2 | 82 | 0.62 | 0.90 | 18 | empty |
| 3 | 245 | 0.60 | 0.80 | 38 | empty |
| 4 | 133 | 0.49 | 0.79 | 25 | empty |
| 5 | 93 | 0.44 | 0.79 | 18 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q553L4
- Elsewhere: UniProt Q553L4 · AlphaFold DB Q553L4
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