Research workbench

AlphaFold monomer V2.0 prediction for maguk P55 subfamily member 2 (Q14168)

Analyse AlphaFold monomer V2.0 prediction for maguk P55 subfamily member 2 (Q14168) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q14168
Type: protein
Length: 576 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0xB698B1521Dfa7d9694657b138eED660997a131C5
Molecule: Maguk P55 subfamily member 2
UniProt: Q14168
Pockets: 7 · best druggability 0.58

Structure

1 distinct chain · 39% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Maguk P55 subfamily member 2	protein	576	39% helix, 19% strand	Q14168

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	427	0.58	0.75	44	empty
2	195	0.52	0.77	29	empty
3	58	0.43	0.82	12	empty
4	105	0.37	0.74	17	empty
5	99	0.35	0.73	16	empty

Compared structures

2E7K · Solution structure of the PDZ domain from Human MAGUK p55 subfamily member 2 · an experimental structure of the same protein · chain A against A, TM-score 0.14
2E7K · Solution structure of the PDZ domain from human maguk P55 subfamily member 2 · an experimental structure of the same protein · chain A against A, TM-score 0.14

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14168
Elsewhere: UniProt Q14168 · AlphaFold DB Q14168

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