Research workbench
AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated protein kinase kinase 1 (Q63980)
Analyse AlphaFold monomer V2.0 prediction for dual specificity mitogen- activated… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q63980
- Type
- protein
- Length
- 393 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x0D671490EE06E75975e90D7F99F73B20BE618744
- Molecule
- Dual specificity mitogen-activated protein kinase kinase 1
- UniProt
- Q63980
- Pockets
- 7 · best druggability 0.77
Structure
1 distinct chain · 42% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dual specificity mitogen-activated protein kinase kinase 1 | protein | 393 | 42% helix, 12% strand | Q63980 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 567 | 0.77 | 0.83 | 63 | empty |
| 2 | 276 | 0.71 | 0.85 | 24 | empty |
| 3 | 413 | 0.65 | 0.79 | 51 | empty |
| 4 | 132 | 0.48 | 0.78 | 20 | empty |
| 5 | 119 | 0.46 | 0.78 | 16 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q63980
- Elsewhere: UniProt Q63980 · AlphaFold DB Q63980
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