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AlphaFold monomer V2.0 prediction for 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (Q9AAW1)

Analyse AlphaFold monomer V2.0 prediction for 5-methyltetrahydropteroyltriglutamate--hom… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9AAW1
Type
protein
Length
777 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xB35df660264f41795De49C83276C108A4ba91ADE
Molecule
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
UniProt
Q9AAW1
Pockets
8 · best druggability 0.80

Structure

1 distinct chain · 46% helix, 13% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseprotein77746% helix, 13% strandQ9AAW1

Pockets

8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111690.800.8191empty
2760.730.9727empty
34300.700.8144empty
42080.570.7922empty
52220.530.7737empty

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