Research workbench
AlphaFold monomer V2.0 prediction for 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (P37355)
Analyse AlphaFold monomer V2.0 prediction for 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P37355
- Type
- protein
- Length
- 252 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
- Molecule
- 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase
- UniProt
- P37355
- Pockets
- 1 · best druggability 0.70
Structure
1 distinct chain · 47% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase | protein | 252 | 47% helix, 15% strand | P37355 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 195 | 0.70 | 0.87 | 35 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4GEG · Crystal Structure of E.coli MenH Y85F Mutant · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4GEG · Crystal structure of E.COLI menh Y85F mutant · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4MYS · 1.4 ångström crystal structure of 2-succinyl-6-hydroxy-2,4- cyclohexadiene-1-carboxylate… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4MYS · 1.4 Angstrom Crystal Structure of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4MYD · 1.37 Angstrom Crystal Structure of E. Coli 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carbo… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4MYD · 1.37 ångström crystal structure of E. COLI 2-succinyl-6-hydroxy-2,4… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4GDM · Crystal Structure of E.coli MenH · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4GDM · Crystal structure of E.COLI menh · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 4GEC · Crystal Structure of E.coli MenH R124A Mutant · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 4GEC · Crystal structure of E.COLI menh R124A mutant · an experimental structure of the same protein · chain A against B, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37355
- Elsewhere: UniProt P37355 · AlphaFold DB P37355
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