Research workbench
AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II transcription subunit 23 (Q5EB59)
Analyse AlphaFold monomer V2.0 prediction for mediator of RNA polymerase II… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q5EB59
- Type
- protein
- Length
- 1,367 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa6fE2E01e4AE83Af8876658629D2e7E885f78aC8
- Molecule
- Mediator of RNA polymerase II transcription subunit 23
- UniProt
- Q5EB59
- Pockets
- 20 · best druggability 0.85
Structure
1 distinct chain · 64% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mediator of RNA polymerase II transcription subunit 23 | protein | 1367 | 64% helix, 1% strand | Q5EB59 |
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1093 | 0.85 | 0.86 | 133 | empty |
| 2 | 1054 | 0.84 | 0.85 | 97 | empty |
| 3 | 136 | 0.78 | 0.95 | 25 | empty |
| 4 | 53 | 0.73 | 0.99 | 19 | empty |
| 5 | 68 | 0.73 | 0.98 | 17 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5EB59
- Elsewhere: UniProt Q5EB59 · AlphaFold DB Q5EB59
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