Research workbench
AlphaFold monomer V2.0 prediction for mRNA cap guanine-N7 methyltransferase (O74880)
Analyse AlphaFold monomer V2.0 prediction for mRNA cap guanine-N7 methyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O74880
- Type
- protein
- Length
- 360 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- MRNA cap guanine-N7 methyltransferase
- UniProt
- O74880
- Pockets
- 6 · best druggability 0.83
Structure
1 distinct chain · 36% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MRNA cap guanine-N7 methyltransferase | protein | 360 | 36% helix, 19% strand | O74880 |
Pockets
6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 814 | 0.83 | 0.85 | 74 | empty |
| 2 | 259 | 0.61 | 0.81 | 30 | empty |
| 3 | 294 | 0.60 | 0.78 | 29 | empty |
| 4 | 221 | 0.47 | 0.74 | 30 | empty |
| 5 | 50 | 0.29 | 0.76 | 19 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74880
- Elsewhere: UniProt O74880 · AlphaFold DB O74880
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