Research workbench
AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase kinase kinase 5 (O35099)
Analyse AlphaFold monomer V2.0 prediction for mitogen-activated protein kinase kinase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O35099
- Type
- protein
- Length
- 1,380 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7012c0b45c68a2c067644b9d3e5DDa06892c6957
- Molecule
- Mitogen-activated protein kinase kinase kinase 5
- UniProt
- O35099
- Pockets
- 15 · best druggability 0.73
Structure
1 distinct chain · 47% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mitogen-activated protein kinase kinase kinase 5 | protein | 1380 | 47% helix, 9% strand | O35099 |
Pockets
15 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 823 | 0.73 | 0.78 | 88 | empty |
| 2 | 185 | 0.69 | 0.87 | 28 | empty |
| 3 | 418 | 0.65 | 0.78 | 28 | empty |
| 4 | 161 | 0.61 | 0.84 | 25 | empty |
| 5 | 251 | 0.60 | 0.80 | 42 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O35099
- Elsewhere: UniProt O35099 · AlphaFold DB O35099
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