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AlphaFold monomer V2.0 prediction for polyunsaturated fatty acid lipoxygenase ALOX15 (P27479)

Analyse AlphaFold monomer V2.0 prediction for polyunsaturated fatty acid lipoxygenase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P27479
Type
protein
Length
663 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xA7381fE9bA15c95992d24BC2A3Bb44aB0Cd83e3f
Molecule
Polyunsaturated fatty acid lipoxygenase ALOX15
UniProt
P27479
Pockets
6 · best druggability 0.75

Structure

1 distinct chain · 45% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APolyunsaturated fatty acid lipoxygenase ALOX15protein66345% helix, 15% strandP27479

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15070.750.8360empty
22010.710.8730empty
32180.590.8028empty
41970.570.8022empty
5950.380.7619empty

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