Research workbench
AlphaFold monomer V2.0 prediction for 3-isopropylmalate dehydratase (O14289)
Analyse AlphaFold monomer V2.0 prediction for 3-isopropylmalate dehydratase (O14289) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O14289
- Type
- protein
- Length
- 758 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xF1437035F7890bd590E2820a667B75cf387314Ef
- Molecule
- 3-isopropylmalate dehydratase
- UniProt
- O14289
- Pockets
- 8 · best druggability 0.71
Structure
1 distinct chain · 36% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-isopropylmalate dehydratase | protein | 758 | 36% helix, 17% strand | O14289 |
Pockets
8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 425 | 0.71 | 0.82 | 56 | empty |
| 2 | 387 | 0.68 | 0.81 | 41 | empty |
| 3 | 678 | 0.68 | 0.76 | 63 | empty |
| 4 | 217 | 0.65 | 0.84 | 48 | empty |
| 5 | 82 | 0.56 | 0.86 | 14 | empty |
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O14289
- Elsewhere: UniProt O14289 · AlphaFold DB O14289
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